New research from a multidisciplinary team is helping to shed light on the mechanisms behind circadian rhythms and offer new hope for dealing with jet lag, insomnia and other sleep disorders. Using innovative cryo-electron microscopy techniques, researchers have identified the structure of the circadian rhythm photosensor and its target in fruit flies (Drosophila melanogaster), one […]
Could a Novel Sleeping Pill Prevent or Delay Alzheimer’s?
Alzheimer’s disease begins when plaques of the protein amyloid beta build up in the brain. After years of amyloid accumulation, a second brain protein, tau, begins to form tangles that are toxic to neurons. People with Alzheimer’s begin to experience cognitive symptoms, such as memory loss, around the time tau involvement is detectable. The brain […]
Migraine and Cluster Headache: The Role of the Circadian Rhythm
Both cluster headaches and migraines have strong connections to the circadian system, the internal clock that regulates body processes, according to a meta-analysis published March 29, 2023 in the online edition of Neurology®, the medical journal of the American Academy of Neurology. Cluster Headache More Severe in Women Cluster headache is a rare headache disorder, […]
Researchers Are Testing a New Drug Designed to Alleviate Heart Failure and Sleep Apnea
Heart failure is a common condition. In Europe, more than 10 million people suffer from cardiac insufficiency. For a variety of reasons, the heart can no longer produce a sufficiently high cardiac output to supply the body with enough oxygen and enable normal metabolism. This can be caused by a reduced pumping power (systolic heart […]
Time-Restricted Eating Alters Gene Expression Throughout the Body
Numerous studies have shown the health benefits of a time-restricted diet, including an increase in lifespan. But how this exactly affects the body at the molecular level, and how these changes interact across multiple organ systems, is not yet fully understood. Salk scientists have been able to show in studies how time-restricted eating affects gene […]
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