Two complementary research articles show that central and peripheral circadian clocks coordinate the daily activity of skin and muscles. Coordination between the two clocks (central and peripheral) ensures 50% of the circadian functions of tissues, including vital processes such as cell cycle, DNA repair, mitochondrial activity and metabolism. Synchronization between the brain’s central and peripheral […]
Researchers Target Neurogenesis in a New Approach to Treating Parkinson’s Disease
Researchers have found a way to better control the preclinical generation of key neurons that are damaged in Parkinson’s disease, revealing a new approach to a disease for which there is no cure and few effective treatments. Efficient Method: Stimulating Stem Cell Differentiation to Produce Neurons in the Midbrain Parkinson’s disease is the second most […]
Circadian Rhythms can Influence the Effectiveness of Medication
Using tiny engineered liver organs derived from human donor cells, researchers found that many genes involved in drug metabolism are under circadian control. These circadian fluctuations affect how much of a drug is available and how effectively the body can break it down. For example, they found that enzymes that break down Tylenol and other […]
Men Versus Women: How Sleep, Circadian Rhythms And Metabolism Differ
A new review of research has examined the key differences in the sleep patterns of women and men, the fluctuations in their body clocks and the impact on their metabolism. The study, published in the journal Sleep Medicine Reviews, highlights the crucial role that gender plays in understanding these factors and suggests that a person’s […]
Infant Gut Microbes Have Their Own Circadian Rhythm And Diet Has Little Influence on How The Microbiome is Composed
The gut microbiome of infants oscillates in a circadian rhythm, even when cultured outside the body. Researchers report in the journal Cell Host & Microbe that this rhythm is detectable as early as two weeks after birth, but becomes more pronounced with increasing age. The findings come from a randomized controlled trial that also showed […]
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